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Diseases of the Retina/Vitreous : Macular Degeneration

What is Age-Related Macular Degeneration (AMD)?

AMD is a common eye disease associated with aging that can gradually destroy the sharp, central vision that is necessary for reading, driving, and recognizing faces. In some people, AMD advances so slowly that it has little effect on their vision as they age. But in others, the disease progresses faster and may lead to a loss of vision in one or both eyes resulting in "legal" blindness. More than 13 million people in the United States have AMD, which is the leading cause of severe vision loss (legal blindness) in the western world.

There are two forms of AMD:

  • Dry AMD - accounts for 90 percent of all cases. Studies suggest that the area at the back of the eye (called the retina) becomes diseased, leading to a gradual loss of central vision.

  • Wet AMD - Although only 10 percent of all people with AMD have the wet form, it accounts for 90 percent of all severe vision loss from the disease. As dry AMD worsens, new blood vessels may begin to grow and cause "wet" AMD. Because these new blood vessels tend to be very fragile, they often will leak blood and fluid which can cause the loss of central vision in a short period of time.

What Causes AMD?

The greatest risk factor is age. People over the age of 60 are clearly at greater risk than other age groups and the risk increases with age. Women, Caucasians, lightly-pigmented people (blond hair, fair skin, blue-eyed) and those who have a family history of the disease also are more likely to develop AMD. Other risk factors may include diet, heart disease, sun exposure and smoking. However, the exact cause is still poorly understood.

What are the Symptoms of AMD?


How AMD can distort your vision

Neither dry nor wet AMD causes any pain. The most common symptom of dry AMD is slightly blurred vision. You may need more light for reading and other tasks. Also, you may find it hard to recognize faces until you are very close to them. As dry AMD worsens, you may see a fuzzy, blurred spot in the center of your vision. Over time, the blurred spot may get bigger and darker, reducing more of your central vision. Early symptoms of wet AMD can include distortion of straight lines and loss of your central vision. These symptoms can develop suddenly, such as overnight.

What You Can Do to Protect Your Vision

If you have dry AMD, you should have a dilated eye examination by your retina doctor at least once each year. In addition, recent research shows that taking certain vitamins containing high levels of vitamin C, vitamin E, beta-carotene, and zinc can slow the progress of the dry type of the disease if you are at high risk for developing advanced stages of AMD. Consult your physician before starting or changing any vitamin or supplement regime.

If you have wet AMD, it is important not to delay evaluations and treatment if your retina specialist has advised you to have it. After treatment, you will need to have frequent eye examinations to detect any recurrence of leaking blood vessels.

People with wet and dry AMD also should monitor their own eyesight at home each day by checking the Amsler grid given to you by Retina Consultants of Southwest Florida® (also available on our web site). You should notify the office immediately if you detect any changes on the Amsler grid card or in your vision.

Making the Most of Your Remaining Vision

Early detection and treatment may reduce the loss of vision from macular degeneration. However, if some loss of vision should occur, it doesn’t have to rob you of life’s simplest pleasures if you learn how to use your remaining eyesight to see your best. Low vision aids, special lenses, or electronic systems and training can maximize your ability to read and perform other activities. The Low Vision Rehabilitation Center of Retina Consultants of Southwest Florida can give you more information about the training and devices available.

What are the Treatment Options?

Unfortunately, there is no cure for either the wet or dry forms of AMD.

For Dry AMD, there are no treatments for this condition however, there are clinical trials underway testing some new treatments. Even though there isn’t a treatment available right now, that doesn’t mean you will lose your sight. Fortunately, dry AMD develops very slowly. Most people with dry AMD are able to lead normal, active lives.

For Wet AMD, there are three main treatment options

  • Medication –These are drugs, usually injected into the eye, to block abnormal blood vessels from growing and leaking blood and fluid. This leakage or bleeding causes loss of vision. In some cases, patients have reported improvements in their vision.
  • Thermal Laser Treatment – This treatment involves aiming a precise laser light beam onto the new blood vessels to destroy them. The major value of the treatment is that it may prevent further vision loss.
  • Photodynamic Therapy (PDT) – This treatment involves injecting a photo-sensitive drug into the arm, which travels to the abnormal blood vessels. The drug then is activated and seals the abnormal blood vessels. This therapy may preserve and, in some cases, improve vision.

Each of these procedures is done in the Retina Consultants office and lasts a short time. Although a person may go home the same day, he or she will need to return for follow-up exams and/or treatments.

How is AMD Detected?

Your eye doctor may suspect AMD if you are over age 60 and have had recent changes in your central vision. To look for signs of the disease, he or she will use eye drops to dilate, or enlarge, your pupils. Dilating the pupils allows your eye doctor to view the back of the eye better. You also may be asked to view an Amsler grid, a pattern that looks like a checkerboard. Early changes of AMD may cause the grid to appear distorted, or have blank areas.

If AMD is suspected, you may need testing, including a fluorescein angiography. In this test, a diagnostic drug is injected into a vein in your arm. As the drug passes through the blood vessels in the retina, pictures are taken that help your eye doctor determine if treatment is needed.

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